Manchester United will be without Kobbie Mainoo and Lisandro Martinez for their Premier League trip to Arsenal in midweek.
The two players will be suspended for the game after receiving yellow cards against Everton on Sunday.
It is Mainoo and Martinez’s fifth booking, resulting in an automatic one-match ban.
This is a major setback for new United manager Ruben Amorim, as Mainoo and Martinez are critical to his tactical scheme.
This will also be Amorim’s first game against one of the top six teams in the league.